The "New Businesses" section in the Democrat and Chronicle lists Ferrara's Pizza coming to 3872 Lyell Rd. That's the address of Carmine's Express, so it looks as if changes may be in the offing.
Speaking of Ferrara's, I remember there used to be a Ferrara's Pizza on Titus Ave., across from the House of Guitars. It was the first place I ever had a Margherita pizza. I don't think I'd consider it a classic Margherita today, as it was made with processed mozzarella and was topped with chopped olives, among other things. But it was damn tasty. I used to drive up from my then-apartment on Rochester's east side to get it.
That Ferrara's later closed and Pudgie's went in there. Now Pudgie's is gone and there's some non-pizza business at the location. Given how many years it's been, I doubt there's any connection between that Ferrara's and the new one, but I'll have to find out.
Pizza Guy correction: a previous version of this post gave the address as that of DiRosato's. DiRosato's is at 3639 Lyell Rd. and is still going strong. I regret the error.